Selma Blair, who is perhaps best known for her work in films like "Legally Blonde" and "Cruel Intentions," played Dr. Kate Wales, the love interest of Charlie Sheen's character and a fellow therapist, on "Anger Management" (via TV Tropes).

However, Blair and Sheen clashed on-set and this friction reportedly came to a head when Blair expressed dissatisfaction with Sheen's professionalism (via Insider). When Sheen got wind of this, he said it was him or Blair — one of them had to go. Given that Sheen was both the star of the show, as well as one of its executive producers, it was Blair who ultimately was given the boot. Sheen then sent Blair a text wherein he "dismissed her from the series and called her a 'c***.'" With co-stars like that, who needs enemies?

For her part, Blair never addressed the situation directly, but rather wrote on Twitter, simply, "I thank you for support and love."

The show produced a grueling two episodes per week and ultimately fulfilled its 100-episode order, at which point it was canceled by FX (via E! Online). However, it still came with quite the payday for Sheen, who was promised between $75 and $200 million for completing 100 episodes, and an even bigger payout should the show perform well in syndication (via TMZ).