In December 2021, Bryton James appeared on the "State of Mind with Maurice Benard" podcast. Hosted by "General Hospital" star Maurice Benard (Sonny Corinthos), the podcast explores mental health struggles. During the interview, the subject of divorce came up. Benard explained, "Some people who get divorced don't want to get married again." James came back with his opinion on the situation, saying, "Yeah, I don't think I would get married again because I have different ideas about the institution of marriage and where it comes from and what it's about."

James also shared that he doesn't believe he will want children, telling Benard, "I've always kind of known that I didn't want to have children, but it hasn't been something as concrete as it is now." James would go on to say something incredibly enlightening: "I know plenty of men who, they don't have to be convinced that they want to have a child and want to leave something behind in that way. It's in them, they just know it ... Those are the people that need to be fathers." James recognizes the sacrifices his parents made for him. "I just know what it takes to enjoy life as much as I did," he explained,"It's a non-stop job." 

His views on having children haven't changed since 2018, when he spoke with Soap Opera Digest about how his father gave up a great job as a musician to keep his family in their homestate. "My parents put so much into my upbringing," James explained. He has remained resolute in his beliefs and his role as Devon Hamilton will be the legacy he leaves behind.